Biopharma & Bioreactors

Flow instruments for a stable gas flow control

Reliable & reproducible mass flow control

For bioreactor manufacturers we have compact gas flow and liquid flow instruments in our product portfolio that can provide you accurate, repeatable and a stable gas and liquid flow. 

Bioreactor customers can benefit from a large dynamic range to measure and control a wide flow range to the bioprocess. The large dynamic range offers systems builders the benefit of reduction in flow device models.  

To serve customers well, we have an extended product portfolio available with gas flow controllers up to 6250 ln/min and liquid flow instruments up to 600 kg/h.

Need Advice

Flow controllers for biopharma processes

Processes in this market can contain valuable biological substances, therefore a continuous process is required. To ensure this, it is helpful to monitor the ‘health’ of the flow instruments, such as: 

  • » Detect temperature variation and measure the internal temperature of the instrument
  • » Response alarm to help you monitor if the flow controller reaches and maintains its setpoint within the specified limits
  • » Power-up alarm to directly return to the last known setpoint after a power failure
  • » Measure & valve out; to detect changes in the setup over time
  • » Monitor pressure of gas supply and bioreactor process (available with FLEXI-FLOW series)
  • » Logging of historical data

What can Bronkhorst offer you?

  • » Wide product range; gas flow controllers up to 6250 ln/min and liquid flow instruments up to 600 kg/h
  • » Worldwide support available for your calibration requests
  • » On-site calibration service, field & remote support and commissioning  
  • » More than 40 years experience in biopharma industry
  • » Instrument with MTBF rating > 130 years

Your benefits

 

  • Large dynamic range up to 1:1000; to enable wide flow range and model reduction
  • High accuracy for optimal control of your Air, N2, O2 and CO2 flows
  • High reliability to avoid downtime 
  • High reproducibility to ensure stable results
  • Intelligent monitoring functions to optimise process control

Downloads

Brochures

Recommended Products

IQ+ FLOW

♦ Ultra Compact
♦ Light weight 100-180 gram
♦ Low power 0.74-2.2 Watt
♦ Multi-channel modules available

FLEXI-FLOW COMPACT

♦ Large dynamic range 1 : 1000
♦ Excellent long-term stability
♦ On-board gas database
♦ Multi-parameter {F+P+T}

EL-FLOW SELECT

♦ Large dynamic range 1 : 1000
♦ High accuracy & repeatability 
♦ Large selection of fieldbusses
♦ Stainless Steel 316 wetted parts

ES-FLOW

♦ CIP cleanable
♦ Self drainable straight sensor tube
♦ Low pressure drop
♦ Certified SS316L wetted parts

Application notes

Gas flow control for bioreactors

Gas flow control for bioreactors

Traditionally benchtop bioreactor processes need dozens of flow controllers. The FLEXI-FLOW Compact reduces that number greatly. Check out how this is done.
Gas dosing in bioreactors

Gas dosing in bioreactors

 
Gas flow controllers play an important role in Bioreactor applications, in benchtop bioreactors, but also in industrial systems. Read our customer note about IQ+FLOW flow controllers in a Bioreactor application for bacterial growth.
Flow control for microorganisms research

 

Flow control for microorganisms research

Flow control is used for microorganisms research. Direct pump control guarantees an accurate & steady flow of aqueous liquid. Read the customer story!
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